Structural analysis of novel DNA origami nanocontainers
AFM reveals the dimensions of nanoscale DNA origami shells, decorated with Tat proteins (red) to promote their uptake into live cells where they can deliver and release protein cargo (green).
Burns JR, Lamarre B, Pyne ALB, Noble JE & Ryadnov MG (2018) DNA Origami Inside-Out Viruses. ACS Synth. Biol. 7: 767–773
AFM determines the dimensions of DNA nanopores (blue) embedded within a nanocontainer drug delivery system
Messager L, Burns JR, Kim J, Cecchin D, Hindley J, Pyne ALB, Gaitzsch J, Battaglia G & Howorka S (2016) Biomimetic Hybrid Nanocontainers with Selective Permeability. Angew. Chem. 128: 11272–11275